Interactions between daily sleep-wake rhythms, γ-secretase, and amyloid-β peptide pathology point to complex underlying relationships
Authors:
- 11 April 2025
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Vol. 1871 (6) , 167840
Abstract
No abstract availableKeywords
Funding Information
- National Institute on Aging (AG068215-03S1)
- National Institute on Aging (T32 AG078110)
- Eli Lilly and Company
- National Institutes of Health
This publication has 85 references indexed in Scilit:
- Association of Short and Long Sleep Duration With Amyloid-β Burden and Cognition in AgingJAMA Neurology, 2021
- Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired AdultsJAMA Network Open, 2021
- Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer DiseaseJAMA Neurology, 2018
- Pittsburgh compound B and the postmortem diagnosis of alzheimer diseaseAnnals of Neurology, 2012
- Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older womenAnnals of Neurology, 2011
- A γ‐secretase inhibitor decreases amyloid‐β production in the central nervous systemAnnals of Neurology, 2009
- Distinct Pools of β-Amyloid in Alzheimer Disease–Affected BrainArchives of Neurology, 2008
- Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane MicrodomainsNeurobiology of Disease, 2002
- The Levels of Soluble versus Insoluble Brain Aβ Distinguish Alzheimer's Disease from Normal and Pathologic AgingExperimental Neurology, 1999
- Alterations in the circadian rest-activity rhythm in aging and Alzheimer's diseaseBiological Psychiatry, 1990