Advanced formulation of intimate lubricating gel for relief of atrophic vaginitis in menopausal women
Authors:
- José Sebastião Cidreira VieiraJVJosé Sebastião Cidreira Vieira
- João Darlon Alves Do AnoJAJoão Darlon Alves Do Ano
- Agustinho Rodrigues PereiraAPAgustinho Rodrigues Pereira
- Makson Rangel de Melo PereiraMPMakson Rangel de Melo Pereira
- Germildo Juvenal MuchaveGMGermildo Juvenal Muchave
- Igor Alves da SilvaISIgor Alves da Silva
- Meirinalva Batista MirandaMMMeirinalva Batista Miranda
- Clenilma Marques BrandãoCBClenilma Marques Brandão
- Antonio José Cantanhede FilhoAntonio José Cantanhede Filho
- Antônio Ernandes Macedo PaivaAPAntônio Ernandes Macedo Paiva
Open Access
- 1 April 2025
- journal article
- Published by Brazilian Journals in Caderno Pedagógico
- Vol. 22 (6) , e15424
Abstract
Climacteric is a period in which several symptoms are triggered in women's health, bringing about profound changes of both positive and negative nature. Among these, the onset of menopause, characterized by the last menstruation, stands out, which results in the reduction of the woman's reproductive capacity. In this sense, intimate lubricating gels were manufactured to combat atrophic vaginitis in climacteric women. This research aimed to prepare and develop intimate lubricating gels based on water and hydroalcoholic extract of medicinal plants (phytoestrogens) aiming at revitalizing the vaginal mucosa and improving the quality of life of climacteric women. The preliminary stability assessment revealed that the gels produced presented organoleptic and physicochemical parameters by the ANVISA Cosmetic Product Stability Guide, given that they showed signs of constancy throughout the evaluation. Therefore, the gels produced are capable of mitigating vaginal dryness, genital burning (dyspareunia), irritation, lack of lubrication and discomfort during sexual intercourse and recurrent urinary infections.Keywords
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