C-Peptide-Measurement: A Simple Method for the Improvement of Specificity
Authors:
- U. KrauseUKU. Krause
- B. von ErdmannBEB. von Erdmann
- W. AtzpodienWAW. Atzpodien
- J. BeyerJBJ. Beyer
- 1 January 1981
- journal article
- Published by Taylor & Francis in Journal of Immunoassay
- Vol. 2 (1) , 33-44
Abstract
Sera containing insulin antibodies and proinsulin give artifactual high readings in C-Peptide measurement. This problem can be circumvented by the removal of antibodies and proinsulin prior to C-Peptide assay. A method is described which enables the removal of antibodies and proinsulin from sera without affecting the C-Peptide determination. Furthermore, this method allows a semiquantitative estimation of proinsulin, provided there is enough cross reactivity of the C-Peptide antibody with proinsulin.Keywords
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