Enhancement of Colonic Drug Absorption by the Transcellular Permeation Route
Authors:
- 1 December 1988
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 5 (12) , 786-789
Abstract
The effects of sodium caprate and sodium caprylate on transcellular permeation routes were examined in rats. The release of membrane phospholipids was significantly increased only by caprate, while...Keywords
This publication has 19 references indexed in Scilit:
- Fluorescence Study of the Membrane-Perturbing Action of Sodium Caprylate as Related to Promotion of Drug AbsorptionJournal of Pharmaceutical Sciences, 1988
- Differences in the promotion mechanism of the colonic absorption of antipyrine, phenol red and cefmetazoleJournal of Pharmacy and Pharmacology, 1987
- Effects of Salicylic Acid on the Permeability of the Plasma Membrane of the Small Intestine of the Rat: a Fluorescence Spectroscopic Approach to Elucidate the Mechanism of Promoted Drug AbsorptionJournal of Pharmaceutical Sciences, 1986
- Comparison of the effects of sodium salicylate, disodium ethylenediaminetetraacetic acid and polyoxyethylene−23−lauryl ether as adjuvants for the rectal absorption of sodium cefoxitinJournal of Pharmacy and Pharmacology, 1985
- Salicylate-promoted permeation of cefoxitin, insulin and phenylalanine across red cell membrane. Possible mechanism.Life Sciences, 1984
- Enhanced Rectal Absorption of Theophylline, Lidocaine, Cefmetazole, and Levodopa by Several AdjuvantsJournal of Pharmaceutical Sciences, 1982
- Barrier function of epitheliaAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1981
- [4] Measurement of protein rotational diffusion in membranes by flash photolysis1978
- Difference in microviscosity induced by different cholesterol levels in the surface membrane lipid layer of normal lymphocytes and malignant lymphoma cellsJournal of Molecular Biology, 1974
- Drug Absorption I: An In Situ Rat Gut Technique Yielding Realistic Absorption RatesJournal of Pharmaceutical Sciences, 1969