Complete Sequence of Broad-Host-Range Plasmid pRIO-5 Harboring the Extended-Spectrum-β-Lactamase Gene bla BES-1
Open Access
- 1 February 2012
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 56 (2) , 1116-1119
Abstract
Broad-host-range plasmid pRIO-5, harboring the extended-spectrum β-lactamase blaBES-1 gene in Serratia marcescens, was fully sequenced. Analysis of the 12,957-bp sequence of this IncP6-type plasmid revealed that the blaBES-1 gene was associated with two copies of the insertion sequence IS26. The promoter responsible for the blaBES-1 expression was hybrid, made of a −35 box located inside the inverted repeat of IS26 and a −10 box inside a remnant of an insertion sequence.Keywords
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