Pulmonary “Hypersensitivity” Reactions Induced by Transfusion of Non-HL-A Leukoagglutinins

Authors:
  • JTJohn S. Thompson
    John S. Thompson
  • CSCharles D. Severson
    Charles D. Severson
  • MPMichael J. Parmely
    Michael J. Parmely
  • BMBarry L. Marmorstein
    Barry L. Marmorstein
  • ASArthur Simmons
    Arthur Simmons

Abstract
In two cases of normovolemic pulmonary edema associated with whole-blood transfusion, clinical manifestations included abrupt onset of chills, fever, tachycardia, dyspnea and cough. Cyanosis and hypotension occurred in the more severe case, and bilateral pulmonary infiltrates without confirmatory evidence of circulatory overload were present in both.

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