Potential Origins of Acute Surgical Site Infections after Orthopedic Surgery: A Prospective Evaluation in Switzerland
Open Access
- 30 October 2026
- journal article
- Published by Hapres in Advances in Geriatric Medicine and Research
- Vol. 8 (4)
Abstract
Background: With an ever-increasing population of elderly orthopedic patients experiencing co-morbidities and immune suppression, the proportion of postoperatively acquired surgical site infections (SSIs) may increase compared to prior decades, where the majority of SSIs were acquired intraoperatively. A comprehensive overview would aid in allocating resources under these conditions. Methods: We examined a prospective database containing data from four prospective randomized clinical interventional trials and surveillance registers. We concentrated on cases of acute SSIs with complete documentation from the 2019–2024 period, during which the number and proportion of clinically frail patients treated at our tertiary center increased significantly. In this assessment, surgeons and Infectious Physicians specialized in orthopedic infections evaluated each SSI episode clinically by searching medical and nursing notes for postoperative events that could possibly be associated with postoperative surgical site infection. Results: Among 370 SSI cases, we estimated that 241 infections (65%) were acquired intraoperatively and 129 (35%) postoperatively. The three most frequent reasons for postoperative SSIs were skin breakdowns, surgical complications (hematoma; dehiscence), and ischemic necrosis. These (new) risk associations differed significantly from the SSI risk reported in the literature on middle-aged orthopedic patients. Conclusions: According to our prospective evaluation, one-third of acute orthopedic SSIs in the last six years might be associated with a postoperative complication. We need to implement additional preventive measures in the postoperative period.Keywords
This publication has 31 references indexed in Scilit:
- A Systematic Review of Complications Following Elective Foot and Ankle SurgeryJournal of Foot and Ankle Research, 2026
- Prevalence and clinical impact of dento-alveolar foci in periprosthetic joint infections: a retrospective cohort study of 213 casesInfection, 2026
- The impact of nutritional status on surgical site infection rates among total joint arthroplasty patients: A systematic reviewAmerican Journal of Infection Control, 2025
- Risk Factors for Surgical Site Infection after Lower Limb Revascularisation Surgery: a Systematic Review and Meta-Analysis of Prognostic StudiesEuropean Journal of Vascular and Endovascular Surgery, 2023
- Early Postoperative Complications in Total Hip and Knee Arthroplasties Before and During the COVID-19 Pandemic: A Retrospective Analysis of 38,234 PatientsArthroplasty Today, 2022
- Association of nutrition status and hospital‐acquired infections in older adult orthopedic trauma patientsJournal of Parenteral and Enteral Nutrition, 2021
- Origin and characteristics of haematogenous periprosthetic joint infectionClinical Microbiology and Infection, 2019
- Smoking is a risk factor of organ/space surgical site infection in orthopaedic surgery with implant materialsInternational Orthopaedics, 2013
- Dressings for the prevention of surgical site infection2011
- Noninfectious Wound Complications in Clean Surgery: Epidemiology, Risk Factors, and Association with Antibiotic UseWorld Journal of Surgery, 2011