Demethylation, Reactivation, and Destabilization of Human Fragile X Full-Mutation Alleles in Mouse Embryocarcinoma Cells
Authors:
- Ulrike SalatUSUlrike Salat
- Horst HameisterHHHorst Hameister
- Walter VogelWVWalter Vogel
- Peter SteinbachPSPeter Steinbach
- 1 September 2001
- journal article
- Published by Elsevier in The American Journal of Human Genetics
- Vol. 69 (3) , 504-515
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Increase of FMRP expression, raised levels of FMR1 mRNA, and clonal selection in proliferating cells with unmethylated fragile X repeat expansions: a clue to the sex bias in the transmission of full mutations?Journal of Medical Genetics, 2000
- Long Uninterrupted CGG Repeats within the First Exon of the Human FMR1 Gene Are Not Intrinsically Unstable in Transgenic MiceGenomics, 1998
- Characterization of the full fragile X syndrome mutation in fetal gametesNature Genetics, 1997
- Heterogeneity of DM kinase repeat expansion in different fetal tissues and further expansion during cell proliferation in vitro: evidence for a causal involvement of methyl-directed DNA mismatch repair in triplet repeat stabilityHuman Molecular Genetics, 1995
- High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndromeHuman Molecular Genetics, 1993
- Fine structure of the human FMR1 geneHuman Molecular Genetics, 1993
- Analysis of full fragile X mutations in fetal tissues and monozygotic twins indicate that abnormal methylation and somatic heterogeneity are established early in developmentAmerican Journal of Medical Genetics, 1992
- Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradoxCell, 1991
- Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndromeCell, 1991
- Metabolic co-operation in HGPRT+ and HGPRT− embryonal carcinoma cellsDevelopmental Biology, 1977