Significant ocular residual astigmatism reduces the effect of orthokeratology lenses in controlling myopia

Authors:
Preprint
Publisher website
Google Scholar
Abstract
Purpose: To investigate the influence of ocular residual astigmatism (ORA) on the therapeutic outcomes of orthokeratology in pediatric myopia management. Methods: In this retrospective cohort study, 60 myopic children (7-12 years) were classified into high-ORA (≥1.00 D; n=30) and low-ORA (0.05). The high-ORA cohort exhibited significantly greater mean axial elongation compared to low-ORA controls at all post-baseline intervals except 1-month (3-month: 0.073±0.082 vs 0.019±0.076 mm, P =0.011; 6-month: 0.139±0.115 vs 0.055±0.098 mm, P =0.003; 12-month: 0.309±0.156 vs 0.137±0.137 mm, P <0.001). Regression analysis revealed baseline ORA magnitude (β=0.219, P <0.001) and spherical equivalent refraction (β=0.043, P =0.038) as positive predictors of annual ΔAL, while patient baseline age showed negative correlation (β=-0.056, P<0.001). Conclusions: High ORA (≥1.00 D) constitutes an independent risk factor for reduced orthokeratology efficacy in pediatric myopia control. This result emphasizes the importance of incorporating ORA assessment into the pre-treatment assessment of orthokeratology lenses fitting. Children with high ORA may benefit from alternative interventions such as peripheral defocus soft contact lenses to optimize myopia management outcomes.

This publication has 29 references indexed in Scilit: