Three nona-2,7-dienoic acid derivatives from saltern derived Micromonospora sp. FXY415
Authors:
- 3 May 2023
- journal article
- research article
- Published by Taylor & Francis in Natural Product Research
- Vol. 38 (15) , 2681-2687
Abstract
Three new compounds, apocimycin A-C, were identified from a saltern-derived Micromonospora sp. strain FXY415, isolated from Dongshi saltern, Fujian, China. Their planar structures and relative configuration were confirmed mainly by analysis of 1D- and 2D- NMR spectra. Three compounds belong to 4,6,8-trimythyl nona-2,7-dienoic acid derivatives, apocimycin A also has a phenoxazine nucleus. Apocimycin A-C exhibited weak cytotoxic and antimicrobial activities. Our research showed again that microbial communities in extreme environments are a potential resource in looking for new and bioactive led compounds. Graphical abstractKeywords
Funding Information
- Fundamental Research Funds for the Central Universities (2011121037)
- Ministry of Science and Technology (2006AA09Z410)
- National High-tech Research and Development Program
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