Molecular Imaging of Inflammation: Current Status
- 12 May 2016
- journal article
- review article
- Published by Society of Nuclear Medicine in Journal of Nuclear Medicine
- Vol. 57 (8) , 1161-1165
Abstract
The ability to image inflammation in vivo can improve our understanding of the pathophysiology underlying various disease etiologies, including cancer, atherosclerosis, and neurodegeneration. A great wealth of preclinical and translational research has been and is currently being developed to decipher the involvement of the immune system in disease pathophysiology, quantify the course of a disease, and visualize the potential detrimental effects of excessive inflammation. Down the road, the ultimate goal is to have clinical noninvasive in vivo imaging biomarkers of inflammation that will help diagnose disease, establish prognosis, and gauge response to preventative and therapeutic strategies.Keywords
This publication has 40 references indexed in Scilit:
- Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease ProbesScientific Reports, 2016
- 64Cu-DOTATATE for Noninvasive Assessment of Atherosclerosis in Large Arteries and Its Correlation with Risk Factors: Head-to-Head Comparison with 68Ga-DOTATOC in 60 PatientsJournal of Nuclear Medicine, 2015
- Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of NeuroinflammationPLOS ONE, 2015
- Superparamagnetic Iron Oxide Nanoparticles in Biomedicine: Applications and Developments in Diagnostics and TherapyRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2013
- Ultrasmall Superparamagnetic Particles of Iron Oxide in Patients With Acute Myocardial InfarctionCirculation: Cardiovascular Imaging, 2012
- Assessment of Disease Activity in Multiple Sclerosis Phenotypes with Combined Gadolinium- and Superparamagnetic Iron Oxide–enhanced MR ImagingRadiology, 2012
- Molecular imaging of microglia/macrophages in the brainGlia, 2012
- Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomographyEuropean Heart Journal, 2011
- The molecular imaging approach to image infections and inflammation by nuclear medicine techniquesAnnals of Nuclear Medicine, 2011
- Use of 99mTc-anti-CD3 scintigraphy in the differential diagnosis of rheumatic diseasesRheumatology, 2010