Antidepressant-like effect of ascorbic acid is associated with the modulation of mammalian target of rapamycin pathway

This publication has 59 references indexed in Scilit:

• Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study
  Nutrition Journal, 2013
• Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress
  Journal of Psychiatric Research, 2012
• mTOR activation is required for the antidepressant effects of mGluR2/3 blockade
  International Journal of Neuropsychopharmacology, 2011
• The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder
  Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2011
• Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
  Molecular Psychiatry, 2011
• Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
  Biological Psychiatry, 2011
• Ethyl Pyruvate Preserves IGF-I Sensitivity toward mTOR Substrates and Protein Synthesis in C2C12 Myotubes
  Endocrinology, 2011
• mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
  Science, 2010
• Ketamine-induced hepatoprotection: the role of heme oxygenase-1
  American Journal of Physiology-Gastrointestinal and Liver Physiology, 2009
• Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression
  Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009