Effect of controlling CO 2 on peripheral hypercapnic chemosensitivity at exercise intensities above the respiratory compensation point

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Abstract
Maintaining end-tidal carbon dioxide ([ ]) at isocapnic levels during supra-respiratory compensation point (RCP) exercise significantly increased the peripheral hypercapnic chemoresponse (PHC) compared with poikilocapnic conditions. However, neither the isocapnic nor poikilocapnic exercise above RCP resulted in a significant increase in PHC compared with lower intensity exercise. Thus, although prestimulus [ ] impacts the PHC, supra-RCP exercise does not further augment the PHC beyond low intensity exercise.
Funding Information
  • Canadian Government | Natural Sciences and Engineering Research Council of Canada (RGPIN-2019-04615)
  • Canada Foundation for Innovation (38432)

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