Ortho-Functionalization of 2-Phenoxypyrimidines via Palladium-Catalyzed C−H Bond Activation
Authors:
- 12 August 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 74 (18) , 7203-7206
Abstract
The palladium-catalyzed direct acetoxylation and arylation of 2-aryloxypyrimidine has been described. The aromatic C−H bonds may be functionalized in moderate to excellent yields providing a facile method for the synthesis of phenol derivatives, which show antimycobacterial and herbicidal activities.Keywords
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