Development of a Bicistronic Yellow Fever Live Attenuated Vaccine with Reduced Neurovirulence and Viscerotropism

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Abstract
Yellow fever (YF) continually spreads and causes epidemics around the world, posing a great threat to human health. The YF live attenuated vaccine 17D is considered the most efficient vaccine available and helps to successfully control disease epidemics.
Funding Information
  • NSFC | National Science Fund for Distinguished Young Scholars (81925025)
  • The Innovative Research Group (81621005)
  • the CAMS Innovation Fund for Medical Science (2019-I2M-5-049)
  • National Natural Science Foundation of China (82101922)
  • National Natural Science Foundation of China (81871632)

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