Resting physiological and perceptual responses to nasal high-flow O 2 therapy in naïve patients with fibrotic interstitial lung disease

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Abstract
In moderately hypoxemic, naive individuals with fibrotic interstitial lung disease, nasal high flow (regardless of O 2 enrichment) lessened resting ventilatory requirements versus room air but increased dyspnea intensity versus conventional O 2 therapy, suggesting dissociation between physiological and perceptual responses in this population. Our findings thus highlight the need for individualized strategies when implementing nasal high flow O 2 therapy in these patients.
Funding Information
  • Fisher and Paykel Healthcare
  • Fonds de dotation AGIR pour les maladies chroniques (AO 2022)
  • Association Nationale de la Recherche et de la Technologie

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