In silico investigation of DNA minor groove binding bibenzimidazoles in the context of UVA phototherapy
- 6 December 2021
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Physical Chemistry Chemical Physics
- Vol. 24 (1) , 112-121
Abstract
DNA-minor groove binding bibenzimidazole ligands, such as ortho-iodoHoechst bind in the minor groove of DNA in AT-rich regions. Upon photodehalogenation of the DNA ligand a carbon-centred radical is formed.Keywords
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