High-Throughput Screening for Positive Allosteric Modulators Identified Potential Therapeutics against Acetylcholinesterase Inhibition
Open Access
- 1 October 2015
- journal article
- Published by Elsevier in SLAS Discovery
- Vol. 20 (9) , 1142-1149
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Potential new therapeutic modality revealed through agent-based modeling of the neuromuscular junction and acetylcholinesterase inhibitionTheoretical Biology and Medical Modelling, 2014
- Limitations and challenges in treatment of acute chemical warfare agent poisoningChemico-Biological Interactions, 2013
- An Ultrasensitive High Throughput Screen for DNA Methyltransferase 1-Targeted Molecular ProbesPLOS ONE, 2013
- Rational Engineering of Enzyme Allosteric Regulation through Sequence Evolution AnalysisPLOS Computational Biology, 2012
- In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicityChemico-Biological Interactions, 2010
- A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus estersChemico-Biological Interactions, 2008
- Acetylcholinesterase inhibitors and Gulf War illnessesProceedings of the National Academy of Sciences, 2008
- Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with AntidotesClinical Pharmacology & Therapeutics, 2007
- The Role of Oximes in the Treatment of Nerve Agent Poisoning in Civilian CasualtiesToxicological Reviews, 2006
- ZINC − A Free Database of Commercially Available Compounds for Virtual ScreeningJournal of Chemical Information and Modeling, 2004