Precision Postoperative Radiotherapy in Sinonasal Carcinomas after Endonasal Endoscopic Surgery
Open Access
Abstract
Radiotherapy plays an important role in the treatment of sinonasal cancer, mainly in the adjuvant setting after surgical resection. Many technological approaches have been described, including intensity-modulated radiotherapy, concomitant chemoradiotherapy, charged particle therapy or combined approaches. The choice is based on general criteria related to the oncological results and morbidity of each technique and their availability, as well as specific criteria related to the tumor (tumor extensions, pathology and quality of margins). The aims of this review are: (i) to provide an overview of the radiotherapy techniques available for the management of sinonasal malignant tumors and (ii) to describe the constraints and opportunities of radiotherapy owing to the recent developments of endonasal endoscopic surgery. The indication and morbidity of the different techniques will be discussed based on a critical literature review.Keywords
This publication has 94 references indexed in Scilit:
- Intensity modulated radiotherapy for sinonasal malignancies with a focus on optic pathway preservationJournal of Hematology & Oncology, 2013
- A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancerJournal of Hematology & Oncology, 2013
- Survival in Sinonasal Melanoma: A Meta-analysisJournal of Neurological Surgery Part B: Skull Base, 2012
- New techniques in radiation therapy for head and neck cancerAnti-Cancer Drugs, 2011
- Intensity-Modulated Radiotherapy for Sinonasal Cancer: Improved Outcome Compared to Conventional RadiotherapyInternational Journal of Radiation Oncology - Biology - Physics (IJROBP), 2010
- TP53 Mutations and Pathologic Complete Response to Neoadjuvant Cisplatin and Fluorouracil Chemotherapy in Resected Oral Cavity Squamous Cell CarcinomaJournal of Clinical Oncology, 2010
- Postoperative intensity‐modulated radiotherapy in sinonasal carcinomaCancer, 2005
- Craniofacial resection for malignant paranasal sinus tumors: Report of an International Collaborative StudyHead & Neck, 2005
- Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck CancerNew England Journal of Medicine, 2004
- Neuroendocrine tumors of the sinonasal tractCancer, 2002