Migraine Surgery: A Plastic Surgery Solution for Refractory Migraine Headache
Authors:
- Bahman GuyuronBGBahman Guyuron
- Paul S. CedernaPCPaul S. Cederna
- 1 January 2011
- journal article
- review article
- Published by Wolters Kluwer Health in Plastic and Reconstructive Surgery
- Vol. 127 (1) , 181-189
Abstract
Migraine headache can be a debilitating condition that confers a substantial burden to the affected individual and to society. Despite significant advancements in the medical management of this challenging disorder, clinical data have revealed a proportion of patients who do not adequately respond to pharmacologic intervention and remain symptomatic. Recent insights into the pathogenesis of migraine headache argue against a central vasogenic cause and substantiate a peripheral mechanism involving compressed craniofacial nerves that contribute to the generation of migraine headache. Botulinum toxin injection is a relatively new treatment approach with demonstrated efficacy and supports a peripheral mechanism. Patients who fail optimal medical management and experience amelioration of headache pain after injection at specific anatomical locations can be considered for subsequent surgery to decompress the entrapped peripheral nerves. Migraine surgery is an exciting prospect for appropriately selected patients suffering from migraine headache and will continue to be a burgeoning field that is replete with investigative opportunities.Keywords
This publication has 77 references indexed in Scilit:
- EFNS guideline on the drug treatment of migraine – revised report of an EFNS task forceEuropean Journal of Neurology, 2009
- When should “chronic migraine” patients be considered “refractory” to pharmacological prophylaxis?Neurological Sciences, 2008
- A Double-Blind, Randomized, Placebo-Controlled Comparison of Botulinum Toxin Type A Injection Sites and Doses in the Prevention of Episodic MigrainePain Medicine, 2007
- Lessons from placebo effects in migraine treatmentThe Journal of Headache and Pain, 2007
- Botulinum Toxin Type A for the Prophylaxis of Chronic Daily Headache: Subgroup Analysis of Patients Not Receiving Other Prophylactic Medications: A Randomized Double‐Blind, Placebo‐Controlled StudyHeadache: The Journal of Head and Face Pain, 2005
- Sporadic Hemiplegic MigraineCephalalgia, 2004
- Acute drug treatment of migraine attackNeurological Sciences, 2004
- Botulinum Toxin A in the Prophylactic Treatment of Migraine – A Randomized, Double-Blind, Placebo-Controlled StudyCephalalgia, 2004
- Diagnosis and Treatment of MigraineMayo Clinic Proceedings, 2002
- Prophylactic Treatment of Classical and Non-Classical Migraine With Metoprolol—a Comparison with PlaceboCephalalgia, 1983