A statistical assessment of clinical equivalence
Author:
- 1 December 1988
- journal article
- research article
- Published by Wiley in Statistics in Medicine
- Vol. 7 (12) , 1267-1277
Abstract
An observed confidence distribution is proposed as a measure of strength of evidence for practically equivalent efficacies of two treatments. The concept is independent of prior opinions about relevant sizes of a difference in efficacy. It also avoids retrospective power calculations for trials with missed recruitment goals and allows combination of the confidence from independent experiments.Keywords
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