Preparation of Silicon–Carbon-Based Dots@Dopamine and Its Application in Intracellular Ag+ Detection and Cell Imaging

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Abstract
A novel nanocomposite, silicon–carbon-based dots@dopamine (Si-CDs@DA) was prepared using (3-aminopropyl) triethoxysilane, glycerol, and dopamine as raw materials via a rapid microwave-assisted irradiation. This type of Si-CDs@DA exhibited ultrabright fluorescence emission (quantum yield of 12.4%) and could response to Ag+ selectively and sensitively. Moreover, the obtained Si-CDs@DA can be further applied in sensing intracellular Ag+ and cell imaging, because of its photostability, salt stability, and low cytotoxicity. This study provides a simple and efficient approach for preparing novel Ag+ fluorescent probes, which could expand the application of carbon nanomaterials in designing related biosensors.
Funding Information
  • National Natural Science Foundation of China (21175069, 21475062, 21505077)
  • Priority Academic Program Development of Jiangsu Higher Education Institutions

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