Flavonoids and chalcones as selective α-glucosidase inhibitors: from enzymatic screening to validation using the human enzyme

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Abstract
The strong α-glucosidase inhibitory activity exhibited by myricetin against both yeast-derived and human enzymes further substantiates the therapeutic potential of polyphenols in diabetes management.
Funding Information
  • Fundação para a Ciência e a Tecnologia (LA/P/0008/2020)
  • Fundação para a Ciência e a Tecnologia (UIDP/50006/2020)
  • Fundação para a Ciência e a Tecnologia (UIDB/50006/2020)
  • Fundação para a Ciência e a Tecnologia (10.54499/2024.01432.BD)
  • European Social Fund Plus (2024.01432.BD)

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