The reaction of cholesterol with ozone and alcohols: a revised mechanism and structure of the principal product
Authors:
- Zdzisław ParyzekZPZdzisław Paryzek
- Jacek MartynowJMJacek Martynow
- Witold SwobodaWSWitold Swoboda
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 4,p. 1222-1223
Abstract
The structure of the product formed in the course of the reaction of cholesterol acetate with ozone in alcohol-containing solvents has been revised. In methanol–chloroform, it is shown to be the hydroperoxide, 3β-acetoxy-5α-hydroperoxy-7β-methoxy-5α-B-homo-6-oxacholestane (8a), and not the previously claimed cyclic hemiperacetal, 3β-acetoxy-5-hydroxy-7a-methoxy-B-dihomo-6,7-dioxacholestane (1; R1= AC, R2= Me).Keywords
This publication has 1 reference indexed in Scilit:
- Ozonization of cholesterolJournal of the American Chemical Society, 1983