The Effect of Isordil and Cyclospasmol on Vascular Spasm Induced in the Basilar Artery of the Cat
Authors:
- Kistler JKJKistler J
- Lees RLRLees R
- Candia GCGCandia G
- Zervas NZNZervas N
- Crowell RCRCrowell R
- Ojemann ROROjemann R
- Watts CWCWatts C
- 1 September 1970
- journal article
- research article
- Published by Wolters Kluwer Health in Stroke
- Vol. 1 (5) , 325-329
Abstract
Vasospasm of the basilar artery of the cat was induced by subarachnoid bleeding and was observed by a transoral approach to the vessel. Intravenous Isordil (2 to 4 mg/kg) given following vasospasm produced vasodilatation with minimal arterial hypotension. Cyclospasmol, administered intravenously after vasospasm or orally prior to vasospasm, was ineffective in relieving or preventing basilar artery spasm.Keywords
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