An HPLC–MS/MS method for simultaneous determination of decitabine and its valyl prodrug valdecitabine in rat plasma
Authors:
- Jin SunJSJin Sun
- Yikun GaoYGYikun Gao
- Ying KongYKYing Kong
- Youjun XuYXYoujun Xu
- Weiru JiaWJWeiru Jia
- Chuanrong LiaoCLChuanrong Liao
- Peng ZhangPZPeng Zhang
- He LianHLHe Lian
- Xiaopeng HanXHXiaopeng Han
- Dongpo LiDLDongpo Li
- Yajie GengYGYajie Geng
- 1 February 2013
- journal article
- Published by Elsevier in Journal of Chromatography B
- Vol. 917-918, 78-83
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Development and validation of a liquid chromatography–tandem mass spectrometry method for quantification of decitabine in rat plasmaJournal of Chromatography B, 2012
- A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapyHaematologica, 2011
- Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studiesJournal of Chromatography B, 2007
- Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)Cancer Chemotherapy and Pharmacology, 2007
- Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemiaBlood, 2006
- Decitabine improves patient outcomes in myelodysplastic syndromesCancer, 2006
- Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5‐aza‐2′‐deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification methodRapid Communications in Mass Spectrometry, 2006
- Chronic myelogenous leukemia in nonlymphoid blastic phaseCancer, 1999
- Sample preparation for the determination of 5-aza-2′-deoxycytidine in plasma by high-performance liquid chromatographyJournal of Chromatography B: Biomedical Sciences and Applications, 1985
- Sample Preparation and Estimation of Plasma Concentration of 3-Deazauridine by High-Performance Liquid ChromatographyTherapeutic Drug Monitoring, 1983