Abstract
Sesquiterpenes are common small-molecule natural products with a wide range of promising applications and are biosynthesized by sesquiterpene synthase (STS). Basidiomycetes are valuable and important biological resources. To date, hundreds of related sesquiterpenoids have been discovered in basidiomycetes, and the biosynthetic pathways of some of these compounds have been elucidated. This review summarizes 122 STSs and 2 fusion enzymes STSs identified from 26 species of basidiomycetes over the past 20 years. The biological functions of enzymes and compound structures are described, and related research is discussed.
Funding Information
  • Innovation and Development Joint Fund of the Natural Science Foundation of Shandong Province (ZR2021LSW022)
  • Shaanxi Key Laboratory of Natural Products & Chemical Biology Open Foundation (SXBPCB 2021001)
  • Fundamental Research Funds for the Central Universities (2572022BD03)

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