Nanoscale Surface Patterns from 103 Single Molecule Helices of Biodegradable Poly(l-lactic acid)
Authors:
- 3 June 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Langmuir
- Vol. 22 (14) , 5969-5973
Abstract
Atomic force microscopy, reflection absorption infrared spectroscopy, and X-ray reflectivity studies reveal that poly(l-lactic acid) molecules in Langmuir−Blodgett (LB) films exist as 103 helices over nearly the entire length of the polymer chain. This feature gives rise to LB films with highly ordered nanoscale smectic liquid crystalline-like surface patterns with low surface roughness and lamellar spacings that scale with molar mass. These studies provide a new approach for controlling surface morphology with a biodegradable polymer commonly used for drug delivery and tissue engineering.Keywords
This publication has 30 references indexed in Scilit:
- Polypyrrole Nanowires Grown from Single Adsorbed Polyelectrolyte MoleculesAngewandte Chemie International Edition, 2005
- Lactic Acid--The Latest Performance-Enhancing DrugScience, 2004
- Compression-Induced Stereocomplexation of Polylactides at the Air/Water InterfaceMacromolecules, 2004
- High-throughput investigation of osteoblast response to polymer crystallinity: influence of nanometer-scale roughness on proliferationBiomaterials, 2004
- Improved Reflectivity Fitting using SERF (Spreadsheet Environment Reflectivity Fitting)Journal of Neutron Research, 1999
- In vitro cell response to differences in poly-L-lactide crystallinityJournal of Biomedical Materials Research, 1996
- Supported Membranes: Scientific and Practical ApplicationsScience, 1996
- Ultrathin layers and supramolecular architecture of isopentylcelluloseMacromolecules, 1995
- Origin of orientation phenomena observed in layered Langmuir-Blodgett structures of hairy-rod polymersMacromolecules, 1992
- Molecular conformation of poly(S‐lactic acid)Biopolymers, 1968