Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis
Open Access
- 26 March 2025
- journal article
- Published by Elsevier in Pharmacological Research
- Vol. 215, 107711
Abstract
No abstract availableKeywords
Funding Information
- Shanghai University of Medicine and Health Sciences (A3-0200-24-311007)
- Fundamental Research Funds for the Central Universities (226-2024-00001)
- National Natural Science Foundation of China (82374136)
This publication has 86 references indexed in Scilit:
- Association of CIITA (rs8048002) and CLEC2D (rs2114870) gene variants and type 1 diabetes mellitusJournal of Diabetes & Metabolic Disorders, 2024
- Ferroptosis and cuproptposis in kidney Diseases: dysfunction of cell metabolismApoptosis, 2023
- Berberine protects mice against type 2 diabetes by promoting PPARγ-FGF21-GLUT2-regulated insulin sensitivity and glucose/lipid homeostasisBiochemical Pharmacology, 2023
- HDL abnormalities in type 2 diabetes: Clinical implicationsAtherosclerosis, 2023
- Effects of supplemental ferulic acid (FA) on survival, growth performance, digestive enzyme activities, antioxidant capacity and lipid metabolism of large yellow croaker (Larimichthys crocea) larvaeFish Physiology and Biochemistry, 2022
- Liver zonation, revisitedHepatology, 2022
- Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosisAdvanced Drug Delivery Reviews, 2021
- Protecting the heart through MK2 modulation, toward a role in diabetic cardiomyopathy and lipid metabolismBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018
- Interplay of adipocyte and hepatocyte: Leptin upregulates hepcidinBiochemical and Biophysical Research Communications, 2018
- Uncoupled iron homeostasis in type 2 diabetes mellitusJournal of Molecular Medicine, 2017