Act Like a Radiologist: Towards Reliable Multi-View Correspondence Reasoning for Mammogram Mass Detection

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Abstract
Mammogram mass detection is crucial for diagnosing and preventing the breast cancers in clinical practice. The complementary effect of multi-view mammogram images provides valuable information about the breast anatomical prior structure and is of great significance in digital mammography interpretation. However, unlike radiologists who can utilize the natural reasoning ability to identify masses based on multiple mammographic views, how to endow the existing object detection models with the capability of multi-view reasoning is vital for decision-making in clinical diagnosis but remains the boundary to explore. In this paper, we propose an anatomy-aware graph convolutional network (AGN), which is tailored for mammogram mass detection and endows existing detection methods with multi-view reasoning ability. The proposed AGN consists of three steps. First, we introduce a bipartite graph convolutional network (BGN) to model the intrinsic geometric and semantic relations of ipsilateral views. Second, considering that the visual asymmetry of bilateral views is widely adopted in clinical practice to assist the diagnosis of breast lesions, we propose an inception graph convolutional network (IGN) to model the structural similarities of bilateral views. Finally, based on the constructed graphs, the multi-view information is propagated through nodes methodically, which equips the features learned from the examined view with multi-view reasoning ability. Experiments on two standard benchmarks reveal that AGN significantly exceeds the state-of-the-art performance. Visualization results show that AGN provides interpretable visual cues for clinical diagnosis.
Funding Information
  • Zhejiang Province Key Research & Development Program (2020C03073, MOST-2018AAA0102004)
  • National Natural Science Foundation of China (61625201, 61527804)
  • DFG (TRR169)
  • NSFC

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