A Matter of Balance: Role of Neurexin and Neuroligin at the Synapse
Authors:
- 5 April 2013
- journal article
- review article
- Published by Springer Nature in Neurochemical Research
- Vol. 38 (6) , 1174-1189
Abstract
Neurexins and neuroligins are synaptic cell adhesion molecules. Neurexins are primary located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic proteins. Since their discovery, the knowledge of neurexins and neuroligins has expanded, implicating them in various neuronal processes, including the differentiation, maturation, stabilization, and plasticity of both inhibitory and excitatory synapses. Here, we review the most recent results regarding the structure and function of these cell adhesion molecules.Keywords
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