Heterozygous familial hypercholesterolemia: Failure of normal allele to compensate for mutant allele at a regulated genetic locus
Authors:
- Joseph L. GoldsteinJGJoseph L. Goldstein
- Mary K. SobhaniMSMary K. Sobhani
- Jerry R. FaustJFJerry R. Faust
- Michael S. BrownMBMichael S. Brown
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Receptor-Mediated Control of Cholesterol MetabolismScience, 1976
- Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycansCell, 1976
- Regulation of the activity of the low density lipoprotein receptor in human fibroblastsCell, 1975
- Cholesterol ester formation in cultured human fibroblasts. Stimulation by oxygenated sterols.Journal of Biological Chemistry, 1975
- Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts.Journal of Clinical Investigation, 1975
- Familial hypercholesterolemiaThe American Journal of Medicine, 1975
- Regulation of RNA polymerase II activity in a mutant rat myoblast cell line resistant to α amanitinNature, 1975
- Expression of the Familial Hypercholesterolemia Gene in Heterozygotes: Mechanism for a Dominant Disorder in ManScience, 1974
- Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human FibroblastsJournal of Biological Chemistry, 1974
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951