Stability of total and free prostate specific antigen in serum submitted to intermittent cold storage conditions
- 1 April 2009
- journal article
- Published by Springer Nature in Indian Journal of Clinical Biochemistry
- Vol. 24 (2) , 166-174
Abstract
The goal of this study was to determine the stability of Total Prostrate Specific antigen (PSA-T) and Free Prostrate Specific Antigen (PSA-F) in archival serum stored at 4°C and −20°C and subjected to temperature shift due to interruption in power supply. Our study showed that PSA-T was stable up to 285 days and PSA-F was stable for 158 days under these conditions. Since power supply interruption is an unavoidable problem in developing nations, our study has implication on the validity of measurement of PSA-T and PSA-F in serum that was not properly stored due to emergency situations and for certain types of retrospective studies.Keywords
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