Camelliin B and nobotanin I, macrocyclic ellagitannin dimers and kelated dimers, and their antitumor activity.

Authors:
  • TYTakashi Yoshida
    Takashi Yoshida
  • TCTong Chou
    Tong Chou
  • KHKumiko Haba
    Kumiko Haba
  • YOYoshiaki Okano
    Yoshiaki Okano
  • TSTetsuro Shingu
    Tetsuro Shingu
  • KMKen-Ici Miyamoto
    Ken-Ici Miyamoto
  • RKRyozo Koshiura
    Ryozo Koshiura
  • TOTakuo Okuda
    Takuo Okuda

Abstract
Camelliin B and nobotanin I, dimeric hydrolyzable tannins of a new class having macrocyclic structures, were isolated from Camellia japonica and Heterocentron roseum, respectively. Nobotanin G and H of the structures related to nobotanin I, were also obtained from H. roseum. Camelliin B and also woodfordin C, a macrocyclic dimer from Woodfordia fruticosa, exhibited marked host-mediated antitumor activities.

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