The Yersinia yop regulon
Authors:
- C. Lambert de RouvroitCRC. Lambert de Rouvroit
- T. MichielsTMT. Michiels
- M. Van BouchauteMBM. Van Bouchaute
- 27 October 1989
- journal article
- review article
- Published by Wiley in Molecular Microbiology
- Vol. 3 (10) , 1455-1459
Abstract
Summary: Growth of yersiniae is restricted at 37°C in the absence of calcium ions. This phenomenon correlates with the massive release of a set of proteins called Yops. Growth restriction and Yops production are governed by a 70 kb plasmid called pYV. yop genes are distributed throughout pYV and constitute a thermoactivated regulon controlled by the gene virF. The transcription activator VirF is a member of a new family of regulators including those of the arabinose and rhamnose operons as well as a regulator of enteric colonization pili. The role of calcium ions on the release of Yops remains largely unknown.Keywords
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