Neuroenergetics and the kinetic design of excitatory synapses
- 1 November 2005
- journal article
- review article
- Published by Springer Nature in Nature Reviews Neuroscience
- Vol. 6 (11) , 841-849
Abstract
Why is the characteristic timescale of neural information processing in the millisecond range, corresponding to a 'clock speed' of about 1 kHz, whereas the clock speed of modern computers is about 3 GHz? Here we investigate how the brain's energy supply limits the maximum rate at which the brain can compute, and how the molecular components of excitatory synapses have evolved properties that are matched to the information processing they perform.Keywords
This publication has 72 references indexed in Scilit:
- Communication in Neuronal NetworksScience, 2003
- An Energy Budget for Signaling in the Grey Matter of the BrainJournal of Cerebral Blood Flow & Metabolism, 2001
- Orientation Preference Patterns in Mammalian Visual CortexNeuron, 2001
- Analog Versus Digital: Extrapolating from Electronics to NeurobiologyNeural Computation, 1998
- Responses of neurons in primary and inferior temporal visual cortices to natural scenesProceedings Of The Royal Society B-Biological Sciences, 1997
- Energy Efficient Neural CodesNeural Computation, 1996
- A Brief History of Time (Constants)Cerebral Cortex, 1996
- The Expensive-Tissue Hypothesis: The Brain and the Digestive System in Human and Primate EvolutionCurrent Anthropology, 1995
- Visual ecology and voltage-gated ion channels in insect photoreceptorsTrends in Neurosciences, 1995
- Axonal trees and cortical architectureTrends in Neurosciences, 1992