A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway
- 1 September 2018
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 155, 275-287
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (J1210026, 31771550, 31400671, 81673380, J1103512, 21761132021, 31571458, 020814380054, 020814380040, 2017YFC0909700)
- Fundamental Research Funds for the Central Universities (J1210026, 31771550, 31400671, 81673380, J1103512, 21761132021, 31571458, 020814380054, 020814380040, 2017YFC0909700)
- National Basic Research Program of China (J1210026, 31771550, 31400671, 81673380, J1103512, 21761132021, 31571458, 020814380054, 020814380040, 2017YFC0909700)
This publication has 40 references indexed in Scilit:
- Chromofungin (CHR: CHGA47-66) is downregulated in persons with active ulcerative colitis and suppresses pro-inflammatory macrophage function through the inhibition of NF-κB signalingBiochemical Pharmacology, 2017
- Cytokines in inflammatory bowel diseaseNature Reviews Immunology, 2014
- miR-141 Regulates colonic leukocytic trafficking by targeting CXCL12β during murine colitis and human Crohn's diseaseGut, 2013
- Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease: an updateExpert Review of Clinical Immunology, 2013
- Normal and disease-related biological functions of Twist1 and underlying molecular mechanismsCell Research, 2011
- Genetics and pathogenesis of inflammatory bowel diseaseNature, 2011
- American Gastroenterological Association Institute Technical Review on Corticosteroids, Immunomodulators, and Infliximab in Inflammatory Bowel DiseaseGastroenterology, 2006
- Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor MetastasisCell, 2004
- Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's diseaseThe Journal of Pathology, 2002
- Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivoNature Medicine, 2000