Heart-type Fatty acid-binding protein in Acute Myocardial infarction Evaluation (FAME): Background and design of a diagnostic study in primary care
Authors:
- Madeleine He Bruins SlotMSMadeleine He Bruins Slot
- Geert Jmg van der HeijdenGHGeert Jmg van der Heijden
- Frans H RuttenFRFrans H Rutten
- Onno P van der SpoelOSOnno P van der Spoel
- E Gijs MastEME Gijs Mast
- Ad C BrederoABAd C Bredero
- Pieter A DoevendansPDPieter A Doevendans
- Jan Fc GlatzJGJan Fc Glatz
- Arno W HoesAHArno W Hoes
Open Access
- 15 April 2008
- journal article
- Published by Springer Nature in BMC Cardiovascular Disorders
- Vol. 8 (1) , 8
Abstract
Currently used biomarkers for cardiac ischemia are elevated in blood plasma after a delay of several hours and therefore unable to detect acute coronary syndrome (ACS) in a very early stage. General practitioners (GPs), however, are often confronted with patients suspected of ACS within hours after onset of complaints. This ongoing study aims to evaluate the added diagnostic value beyond clinical assessment for a rapid bedside test for heart-type fatty-acid binding protein (H-FABP), a biomarker that is detectable as soon as one hour after onset of ischemia.Keywords
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