Through the eye of the needle: recent advances in understanding biopolymer translocation

Authors:
  • GBGerard T Barkema
    Gerard T Barkema
  • AKAnatoly B Kolomeisky
    Anatoly B Kolomeisky

Abstract
In recent years polymer translocation, i.e., transport of polymeric molecules through nanometer-sized pores and channels embedded in membranes, has witnessed strong advances. It is now possible to observe single-molecule polymer dynamics during the motion through channels with unprecedented spatial and temporal resolution. These striking experimental studies have stimulated many theoretical developments. In this short theory-experiment review, we discuss recent progress in this field with a strong focus on non-equilibrium aspects of polymer dynamics during the translocation process.
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