LombardIMA: a regional registry for coronary angioplasty in ST-elevation myocardial infarction

Authors:
  • AMAlessandro Martinoni
    Alessandro Martinoni
  • SKSilvio Klugmann
    Silvio Klugmann
  • RZRoberto Zanini
    Roberto Zanini
  • MOMarco Onofri
    Marco Onofri
  • GGGiulio Guagliumi
    Giulio Guagliumi
  • CFCesare Fiorentini
    Cesare Fiorentini
  • CLCorrado Lettieri
    Corrado Lettieri
  • GBGuido Belli
    Guido Belli
  • EPEmanuela Piccaluga
    Emanuela Piccaluga
  • NCNicoletta De Cesare
    Nicoletta De Cesare
  • MDMaurizio D'URbano
    Maurizio D'URbano

Abstract
We sought to provide information about the current status of this treatment with a registry collecting data in Lombardy, the most densely populated region in Italy, with widespread availability of cathlabs and a well-established network for the treatment of STEMI. Methods and results Patient enrolment was performed by 32 hub centres recruiting 3901 STEMI patients who underwent PCI procedures within 12 h of the onset of symptoms, of whom 3317 patients underwent primary PCI, 376 ‘facilitated’ PCI, and 208 rescue PCI in cathlabs located, in 77% of cases, in the same hospital of admission. In-hospital and 30-day total death were 4.4 and 6.6%, respectively. At multivariate analysis independent negative predictors of 30-day mortality were Killip class 3–4, number of involved ECG leads, chronic renal failure and age, whereas positive predictors were ST resolution more than 50% and postprocedural grade 3 thrombolysis in myocardial infarction flow. Conclusions LombardIMA PCI registry enrolled STEMI patients representing a real-world population treated with PCI. Findings presented in this study may provide a benchmark for similar registries undertaken in other Italian regions and may be helpful to assess future possible developments of care for STEMI patients....

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