Low Prevalence of Germline CDKN2A and CDK4 Mutations in Patients With Early-Onset Melanoma
Authors:
- Hensin TsaoHTHensin Tsao
- Xue ZhangXZXue Zhang
- Kimberly KwitkiwskiKKKimberly Kwitkiwski
- Dianne M. FinkelsteinDFDianne M. Finkelstein
- Arthur J. SoberASArthur J. Sober
- Frank G. HaluskaFHFrank G. Haluska
Open Access
- 1 September 2000
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 136 (9) , 1118-1122
Abstract
CUTANEOUS melanoma has grown rapidly in incidence among fair-skinned populations over the past several decades. In 2000, an estimated 47,700 cases of cutaneous melanoma will occur in the United States, with 7700 deaths as a result.1 Although the cause of cutaneous melanoma is unknown, both genetic factors and environmental carcinogens, such as sun exposure,2 contribute to its development.Keywords
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