Age‐standardized incidence rates of primordial cyst (keratocyst) on the Witwatersrand

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Abstract
Cases of primordial cysts derived from the records of all the hospital pathology departments and private pathology practices on the Witwatersrand, South Africa, were recorded for the 10 yr period, 1965-74. The population at risk (1970 census) was 974,390 Whites and 1,567,280 Blacks. Age-specific morbidity rates for each sex and race were calculated and age-standardized incidence rates standardized against African, world and European standard populations. The age-standardized incidence rates for primordial cysts, standardized against a world standard population, per million/yr are 0.61, 0, 4.86 and 3.50 for Black males and females and White males and females, respectively. In the population at risk, primordial cysts are much more common in Whites than in Blacks, the incidence being 8 .times. higher in White males than in Black males. There is a bimodal age distribution but with a higher incidence of the cyst in the age group 50-64 yr than previously suspected. This may be either because a substantial number of cases remain undiagnosed for many years or because there are 2 groups of primordial cyst; one which is triggered in young patients and the other in older patients.

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