Obesitiy: Its Complications and Available Medications
Open Access
- 12 January 2020
- journal article
- review article
- Published by Kocaeli Universitesi Saglik Bilimleri Dergisi in Kocaeli Üniversitesi Sağlık Bilimleri Dergisi
- Vol. 6 (1) , 68-76
Abstract
Obesity is one of the common metabolic diseases which is tremendously on the rise. According to the World Health Organization (WHO), the number of patients has increased three times since 1975. A person with Body Mass Index (BMI) equal to or higher than 30.0 is considered obese. Previously considered only as a cosmetic concern, obesity has now been shown to be an aggravating element for various diseases and disorders including diabetes and cardiovascular diseases (CVD). The most common drugs subscribed by physicians include orlistat, rimonabant, liraglutide and sibutramine which have been proven to be effective to reduce body fat in patients. However, in the long run, patients have complained about symptoms which are mild like nausea, insomnia and dizziness to severe complications such as increase in risk of heart attack or stroke. The following review provides insights about synthetic drugs, their classification and their side-effects on human health. Furthermore, a gist of natural products i.e. phytochemicals that can be used as an alternative to these synthetic drugs has also been discussed in the review.Keywords
This publication has 47 references indexed in Scilit:
- Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in RatsISRN Pharmacology, 2011
- Rise and fall of anti-obesity drugsWorld Journal of Diabetes, 2011
- Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic reviewInternational Journal of Obesity, 2010
- Interactions Between Obesity and Obstructive Sleep ApneaChest, 2010
- The Medical Risks of ObesityPostgraduate Medicine, 2009
- Harmonizing the Metabolic SyndromeCirculation, 2009
- Curcumin Inhibits Adipogenesis in 3T3-L1 Adipocytes and Angiogenesis and Obesity in C57/BL MiceThe Journal of Nutrition, 2009
- Proposed mechanisms of (−)-epigallocatechin-3-gallate for anti-obesityChemico-Biological Interactions, 2007
- Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: The Rotterdam StudyAnnals of the Rheumatic Diseases, 2007
- Insulin resistance and pancreatic cell failureJournal of Clinical Investigation, 2006