COBRA methods and metabolic drug targets in cancer
Open Access
- 7 November 2017
- journal article
- research article
- Published by Taylor & Francis in Molecular & Cellular Oncology
- Vol. 5 (1) , e1389672
Abstract
The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis) framework for metabolic networks, to perform this task. Current and future steps are presented.Keywords
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