Metabolism of nifedipine by placental CYP19A1 and competitive inhibition by chlorpromazine
Authors:
- 17 October 2025
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 242 (Pt 4) , 117425
Abstract
No abstract availableKeywords
Funding Information
- Science and Technology Commission of Shanghai Municipality (CNKW2024Y34)
- Science and Technology Commission of Shanghai Municipality (RCJD2022S06)
- National Natural Science Foundation of China (82274010)
- East China Normal University (2022JKXYD09004)
This publication has 41 references indexed in Scilit:
- Use of physiologically‐based pharmacokinetic modeling to understand the effect of omeprazole administration on the pharmacokinetics of oral extended‐release nifedipineCPT: Pharmacometrics & Systems Pharmacology, 2023
- The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemiaActa Pharmaceutica Sinica B, 2022
- The etiology of preeclampsiaAmerican Journal of Obstetrics and Gynecology, 2022
- An integrated model of preeclampsia: a multifaceted syndrome of the maternal cardiovascular-placental-fetal arrayAmerican Journal of Obstetrics and Gynecology, 2022
- Eclampsia in the 21st centuryAmerican Journal of Obstetrics and Gynecology, 2022
- Nifedipine disturbs fetal cardiac function during hypoxemia in a chronic sheep model at near term gestationAmerican Journal of Obstetrics and Gynecology, 2021
- Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysisAmerican Journal of Obstetrics and Gynecology, 2020
- A novel GC-MS methodology to evaluate aromatase activity in human placental microsomes: a comparative study with the standard radiometric assayAnalytical and Bioanalytical Chemistry, 2019
- The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy?Birth Defects Research, 2019
- Time-dependent expression pattern of cytochrome P450 epoxygenases and soluble epoxide hydrolase in normal human placentaActa Histochemica, 2018