Visualization of Bacterial Genes in Action
Authors:
- 24 July 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 169 (3943) , 392-395
Abstract
The morphology of active structural and putative ribosomal RNA genes was observed by electron microscopy after lysis of fragile Escherichia coli cells. Conclusions drawn are: most of the chromosome is not genetically active at any one instant; translation is completely coupled with transcription; the 16 S and 23 S ribosomal RNA cistrons occur in tandem, in regions which are widely spaced on the chromosome.Keywords
This publication has 23 references indexed in Scilit:
- Portrait of a geneJournal of Cellular Physiology, 1969
- RNA chain growth rates in Escherichia coliJournal of Molecular Biology, 1969
- RNA chain growth-rate in Escherichia coliJournal of Molecular Biology, 1968
- Titration of the gene sites on DNA by DNA-RNA hybridizationJournal of Molecular Biology, 1968
- Polyribosome metabolism in Escherichia coliJournal of Molecular Biology, 1967
- Transcription of the tryptophan operon in polarity mutants of Escherichia coliJournal of Molecular Biology, 1967
- Relative transcription activity of different segments of the genome throughout the cell division cycle of Escherichia coli. The mapping of ribosomal and transfer RNA and the determination of the direction of replicationJournal of Molecular Biology, 1967
- Electron stains II: Electron microscopic studies on the visibility of stained DNA moleculesJournal of Molecular Biology, 1961
- ELECTRON MICROSCOPY OF DNA MOLECULES "STAINED" WITH HEAVY METAL SALTSJournal of Cell Biology, 1961
- The Absence of Histone in the Bacterium Escherichia coli Journal of Cell Biology, 1959