Lipopolysaccharide (LPS)-induced septic shock causes profound changes in myocardial energy metabolites in pigs
- 25 September 2018
- journal article
- research article
- Published by Springer Nature in Metabolomics
- Vol. 14 (10) , 131
Abstract
Energy deficiency is a cause for myocardial dysfunction during septic shock. In rodents, septic shock decreases the oxidation of long-chain fatty acids and glucose in the myocardium causing energy deficiency. However, the effect of septic shock on myocardial energy metabolites in large animals and human is unknown.Keywords
Funding Information
- CH Foundation
- Texas Tech University Health Sciences Center
- FP7 Ideas: European Research Council (281854)
- Secretaria Xeral de Investigación e Desenvolvemento, Xunta de Galicia (2015-CP079)
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