Functional evaluation of vandetanib metabolism by CYP3A4 variants and potential drug interactions in vitro
- 1 December 2021
- journal article
- research article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 350, 109700
Abstract
No abstract availableKeywords
Funding Information
- National Key Research and Development Program of China (2020YFC2008301)
- National Natural Science Foundation of China (81973397)
- Ministry of Science and Technology of the People's Republic of China
This publication has 41 references indexed in Scilit:
- Applications of CYP450 Testing in the Clinical SettingMolecular Diagnosis & Therapy, 2013
- Pharmacokinetics and Tolerability of Vandetanib in Chinese Patients With Solid, Malignant Tumors: An Open-Label, Phase I, Rising Multiple-Dose StudyClinical Therapeutics, 2011
- Polymorphism of human cytochrome P450 enzymes and its clinical impactDrug Metabolism Reviews, 2009
- Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspectsPharmacology & Therapeutics, 2007
- Clinical implications of pharmacogenetics of cytochrome P450 drug metabolizing enzymesBiochimica et Biophysica Acta (BBA) - General Subjects, 2007
- Bench to Bedside: Pharmacogenomics, Adverse Drug Interactions, and the Cytochrome P450 SystemAcademic Emergency Medicine, 2005
- ScreeningCYP3Asingle nucleotide polymorphisms in a Han Chinese population with a genotyping chipPharmacogenomics, 2005
- The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å ResolutionJournal of Biological Chemistry, 2004
- Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and ProgesteroneScience, 2004
- MULTISITE KINETIC ANALYSIS OF INTERACTIONS BETWEEN PROTOTYPICAL CYP3A4 SUBGROUP SUBSTRATES: MIDAZOLAM, TESTOSTERONE, AND NIFEDIPINEDrug Metabolism and Disposition, 2003