Soft Tissue Special Issue: Gnathic Fibro-Osseous Lesions and Osteosarcoma
Authors:
- 16 January 2020
- journal article
- research article
- Published by Springer Nature in Head and Neck Pathology
- Vol. 14 (1) , 70-82
Abstract
Gnathic fibro-osseous lesions are a diverse group of disease processes which share overlapping microscopic features characterized by fibroblastic stroma with variable cellularity and a range of bone forming pathological processes leading to woven, sclerotic and cementum-like structures. Some of the lesions are unique to craniofacial location and a combination of clinical, radiological and pathological correlation is often necessary for diagnostic accuracy. Gnathic osteosarcomas are rare tumors with differences in age distribution and behavior as compared to osteosarcoma of long bones. This review will discuss the clinicopathological and radiological features of gnathic fibro-osseous lesions and osteosarcoma with updates on current genetics and molecular pathogenesis.Keywords
This publication has 59 references indexed in Scilit:
- Clinical guidelines for the management of craniofacial fibrous dysplasiaOrphanet Journal of Rare Diseases, 2012
- Potent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune–Albright Syndrome and fibrous dysplasia of boneBone, 2011
- Well-differentiated Osteosarcoma of the Jaw BonesAmerican Journal of Surgical Pathology, 2010
- Primary Rosai-Dorfman Disease of BoneAmerican Journal of Surgical Pathology, 2010
- SAPHO syndrome with ankylosis of the temporomandibular jointInternational Journal of Oral and Maxillofacial Surgery, 2009
- International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly personsInternational Journal of Cancer, 2009
- Benign Fibro-Osseous Lesions of the Craniofacial Complex A ReviewHead and Neck Pathology, 2008
- Evolution of the vertebrate jaw: comparative embryology and molecular developmental biology reveal the factors behind evolutionary noveltyJournal of Anatomy, 2004
- HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndromeNature Genetics, 2002
- Chronic multifocal osteomyelitis, a new recessive mutation on Chromosome 18 of the mouseGenomics, 1991