Evidence for dual physiological forms of ergosterol in Saccharomyces cerevisiae
Authors:
- 1 October 1967
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 70 (2) , 161-168
Abstract
Data obtained from acid hydrolysis and extraction of yeast have demonstrated that routine saponification does not recover total sterol from the cells. This suggests the existence of a form of ergosterol resistant to saponification. Time course analyses of sterol synthesis by resting cell suspensions reveal an inverse relationship between the amounts of base labile and acid labile forms of sterol. These data give strong presumptive evidence for dual forms of ergosterol which are interconvertible according to the respiratory state of the cell.Keywords
This publication has 10 references indexed in Scilit:
- Studies on the Biosynthesis of Ergosterol in YeastJournal of Biological Chemistry, 1967
- Correlation of membrane bound succinate dehydrogenase with the occurrence of mitochondrial profiles in Saccharomyces cerevisiaeBiochemical and Biophysical Research Communications, 1966
- Transmethylation products as intermediates in ergosterol biosynthesis in yeastBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1965
- Development of respiration in yeast grown anaerobically on different carbon sourcesBiochemical Journal, 1964
- Influence of Ergosterol on the Physiology and the Ultra-Structure of Saccharomyces CerevisiaeNature, 1964
- A relationship between ergosterol and respiratory competency in yeastJournal of Cellular and Comparative Physiology, 1963
- Cleavage of Steroidal Digitonides in Dimethyl SulfoxideThe Journal of Organic Chemistry, 1962
- SOME FACTORS AFFECTING STEROL FORMATION IN SACCHAROMYCES CEREVISIAEJournal of Bacteriology, 1962
- Effect of Temperature on Sterol Metabolism in YeastJournal of Cellular and Comparative Physiology, 1962
- S-ADENOSYLMETHIONINE AND ERGOSTEROL SYNTHESIS1Journal of the American Chemical Society, 1958